Fanconi anemia, complementation group M (FANCM) - coding DNA reference sequence

(used for mutation description)

(last modified May 1, 2014)


This file was created to facilitate the description of sequence variants in the FANCM gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NC_000014.8, covering FANCM transcript NM_020937.2.


Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
                               .         .         .                g.1039
                      gagttttgtgcgaaggaaaccgatggggatcggaaccgt       c.-61

 .         .         .         .         .         .                g.1099
 agcggttgagctgctgctgctacggatatctgacagaagccttcggtggttgtcggccta       c.-1

          .         .         .         .         .         .       g.1159
 ATGAGCGGACGGCAAAGAACGCTTTTTCAGACGTGGGGCTCAAGTATCTCCCGATCATCT       c.60
 M  S  G  R  Q  R  T  L  F  Q  T  W  G  S  S  I  S  R  S  S         p.20

          .         .         .         .         .         .       g.1219
 GGGACTCCGGGTTGCAGCTCCGGAACTGAGCGACCTCAGAGCCCTGGCAGCTCCAAGGCG       c.120
 G  T  P  G  C  S  S  G  T  E  R  P  Q  S  P  G  S  S  K  A         p.40

          .         .         .         .         .         .       g.1279
 CCTTTGCCAGCAGCAGCGGAGGCTCAGCTGGAGTCGGACGATGATGTGTTGCTTGTCGCG       c.180
 P  L  P  A  A  A  E  A  Q  L  E  S  D  D  D  V  L  L  V  A         p.60

          .         .         .         .         .         .       g.1339
 GCGTACGAGGCTGAGCGGCAGTTGTGTCTAGAGAATGGCGGGTTCTGCACCTCCGCGGGC       c.240
 A  Y  E  A  E  R  Q  L  C  L  E  N  G  G  F  C  T  S  A  G         p.80

          .         .         .         .         .         .       g.1399
 GCCCTGTGGATTTACCCTACCAATTGCCCAGTGCGGGACTACCAGCTGCACATTTCCCGG       c.300
 A  L  W  I  Y  P  T  N  C  P  V  R  D  Y  Q  L  H  I  S  R         p.100

          .         .         .         .         .         .       g.1459
 GCTGCTCTGTTTTGCAATACGCTGGTGTGTCTGCCTACCGGACTGGGAAAGACCTTTATT       c.360
 A  A  L  F  C  N  T  L  V  C  L  P  T  G  L  G  K  T  F  I         p.120

          .         .         .         .         .         .       g.1519
 GCCGCCGTGGTCATGTACAATTTCTACCGCTGGTTCCCTTCAGGAAAGGTGGTCTTCATG       c.420
 A  A  V  V  M  Y  N  F  Y  R  W  F  P  S  G  K  V  V  F  M         p.140

          .         .         .         .         .         .       g.1579
 GCCCCAACGAAACCCTTGGTGACACAGCAGATCGAGGCTTGCTACCAGGTGATGGGTATC       c.480
 A  P  T  K  P  L  V  T  Q  Q  I  E  A  C  Y  Q  V  M  G  I         p.160

          .         .         | 02         .         .         .    g.2168
 CCGCAATCCCACATGGCCGAAATGACAG | GGTCTACACAAGCTTCCACCAGGAAGGAAATA    c.540
 P  Q  S  H  M  A  E  M  T  G |   S  T  Q  A  S  T  R  K  E  I      p.180

          .         .         .         .         .         .       g.2228
 TGGTGCAGTAAGAGAGTGCTTTTTCTTACACCTCAGGTCATGGTAAATGACCTTTCTAGA       c.600
 W  C  S  K  R  V  L  F  L  T  P  Q  V  M  V  N  D  L  S  R         p.200

          .         .         .         .         .         .       g.2288
 GGAGCTTGTCCCGCTGCTGAAATAAAGTGTTTAGTTATTGATGAAGCTCATAAAGCTCTC       c.660
 G  A  C  P  A  A  E  I  K  C  L  V  I  D  E  A  H  K  A  L         p.220

          .         .  | 03      .         .         .         .    g.5738
 GGAAACTATGCTTATTGCCAG | GTTGTAAGAGAACTAGTCAAATATACAAATCACTTTAGA    c.720
 G  N  Y  A  Y  C  Q   | V  V  R  E  L  V  K  Y  T  N  H  F  R      p.240

          .         .         .          | 04        .         .    g.13925
 ATCTTGGCTCTAAGTGCCACACCAGGTAGTGATATAAAG | GCTGTGCAACAAGTTATTACT    c.780
 I  L  A  L  S  A  T  P  G  S  D  I  K   | A  V  Q  Q  V  I  T      p.260

          .         .         .         .         .         .       g.13985
 AACCTGCTAATTGGGCAGATAGAGCTTCGTTCTGAAGATTCTCCAGATATTTTGACATAT       c.840
 N  L  L  I  G  Q  I  E  L  R  S  E  D  S  P  D  I  L  T  Y         p.280

          .         .         .         .         .         .       g.14045
 TCTCATGAAAGAAAAGTTGAAAAGCTTATTGTTCCGCTTGGTGAAGAACTTGCAGCCATC       c.900
 S  H  E  R  K  V  E  K  L  I  V  P  L  G  E  E  L  A  A  I         p.300

          .         | 05         .         .         .         .    g.16506
 CAAAAGACCTATATCCAG | ATTTTGGAATCATTTGCTCGTTCTTTGATTCAGAGGAATGTT    c.960
 Q  K  T  Y  I  Q   | I  L  E  S  F  A  R  S  L  I  Q  R  N  V      p.320

          .         .         .         .         .         .       g.16566
 TTGATGAGAAGGGATATCCCAAATCTAACAAAATATCAGATAATTCTGGCAAGAGATCAG       c.1020
 L  M  R  R  D  I  P  N  L  T  K  Y  Q  I  I  L  A  R  D  Q         p.340

          .         .         . | 06       .         .         .    g.19017
 TTTAGGAAAAACCCATCTCCGAATATTGTG | GGAATACAACAAGGCATAATCGAGGGAGAG    c.1080
 F  R  K  N  P  S  P  N  I  V   | G  I  Q  Q  G  I  I  E  G  E      p.360

          .         .         .         .         .         .       g.19077
 TTTGCTATTTGTATTAGTTTATATCATGGTTATGAATTATTGCAGCAAATGGGAATGAGA       c.1140
 F  A  I  C  I  S  L  Y  H  G  Y  E  L  L  Q  Q  M  G  M  R         p.380

          .         .         .         .    | 07    .         .    g.19781
 TCATTATATTTCTTCCTTTGTGGAATTATGGATGGAACTAAAG | GGATGACACGGTCAAAA    c.1200
 S  L  Y  F  F  L  C  G  I  M  D  G  T  K  G |   M  T  R  S  K      p.400

          .         .         .         .         .         .       g.19841
 AATGAACTTGGCCGAAATGAAGACTTCATGAAACTCTATAATCATCTAGAGTGTATGTTT       c.1260
 N  E  L  G  R  N  E  D  F  M  K  L  Y  N  H  L  E  C  M  F         p.420

          .         .         .         .          | 08        .    g.20451
 GCACGTACACGTAGTACTTCAGCAAATGGTATTTCTGCTATCCAACAAG | GAGATAAAAAT    c.1320
 A  R  T  R  S  T  S  A  N  G  I  S  A  I  Q  Q  G |   D  K  N      p.440

          .         .         .         .         .         .       g.20511
 AAAAAATTTGTTTATAGTCATCCAAAGTTAAAGAAATTAGAAGAAGTTGTAATTGAACAC       c.1380
 K  K  F  V  Y  S  H  P  K  L  K  K  L  E  E  V  V  I  E  H         p.460

          .       | 09 .         .         .         .         .    g.24207
 TTCAAGTCATGGAATG | CTGAAAACACTACTGAAAAGAAACGTGATGAGACCCGAGTTATG    c.1440
 F  K  S  W  N  A |   E  N  T  T  E  K  K  R  D  E  T  R  V  M      p.480

          .         .         .         .         .         .       g.24267
 ATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAG       c.1500
 I  F  S  S  F  R  D  S  V  Q  E  I  A  E  M  L  S  Q  H  Q         p.500

          .         .         .         .         .         .       g.24327
 CCAATTATTAGAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTT       c.1560
 P  I  I  R  V  M  T  F  V  G  H  A  S  G  K  S  T  K  G  F         p.520

          .         .  | 10      .         .         .         .    g.29465
 ACCCAGAAGGAGCAACTGGAG | GTAGTGAAACAGTTTCGTGACGGTGGTTACAACACGCTG    c.1620
 T  Q  K  E  Q  L  E   | V  V  K  Q  F  R  D  G  G  Y  N  T  L      p.540

          .         .         .         .         .         .       g.29525
 GTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGT       c.1680
 V  S  T  C  V  G  E  E  G  L  D  I  G  E  V  D  L  I  I  C         p.560

          .         .         .         .         .         .       g.29585
 TTTGATTCCCAGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAA       c.1740
 F  D  S  Q  K  S  P  I  R  L  V  Q  R  M  G  R  T  G  R  K         p.580

          .         .         .         .         | 11         .    g.32029
 CGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGACGAGAGGAACGT | ATTTATAATCAG    c.1800
 R  Q  G  R  I  V  I  I  L  S  E  G  R  E  E  R   | I  Y  N  Q      p.600

          .         .         .         .         .         .       g.32089
 AGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCAT       c.1860
 S  Q  S  N  K  R  S  I  Y  K  A  I  S  S  N  R  Q  V  L  H         p.620

          .         .         .         .         .         .       g.32149
 TTTTACCAAAGAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATG       c.1920
 F  Y  Q  R  S  P  R  M  V  P  D  G  I  N  P  K  L  H  K  M         p.640

          .         .         .         .         .         .       g.32209
 TTCATCACACATGGTGTCTATGAACCAGAGAAGCCTTCTCGGAACTTGCAGCGAAAGTCA       c.1980
 F  I  T  H  G  V  Y  E  P  E  K  P  S  R  N  L  Q  R  K  S         p.660

          .         .   | 12     .         .         .         .    g.35694
 TCTATCTTTTCCTATAGGGATG | GAATGAGGCAAAGTAGCCTAAAGAAAGATTGGTTCTTA    c.2040
 S  I  F  S  Y  R  D  G |   M  R  Q  S  S  L  K  K  D  W  F  L      p.680

          .         .         .         .         .         .       g.35754
 TCAGAAGAAGAATTTAAATTATGGAACAGACTTTATAGATTAAGGGACAGTGATGAAATT       c.2100
 S  E  E  E  F  K  L  W  N  R  L  Y  R  L  R  D  S  D  E  I         p.700

          .         .         .         .         .         .       g.35814
 AAAGAGATAACATTGCCTCAAGTTCAGTTTTCTTCTTTACAAAATGAGGAAAACAAACCA       c.2160
 K  E  I  T  L  P  Q  V  Q  F  S  S  L  Q  N  E  E  N  K  P         p.720

  | 13       .         .         .         .         .         .    g.38182
  | GCTCAAGAATCAACCACTGGAATTCATCAACTCTCTCTCTCTGAATGGAGACTGTGGCAA    c.2220
  | A  Q  E  S  T  T  G  I  H  Q  L  S  L  S  E  W  R  L  W  Q      p.740

          .         .         .         .         .         .       g.38242
 GATCATCCTTTGCCTACACATCAAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGC       c.2280
 D  H  P  L  P  T  H  Q  V  D  H  S  D  R  C  R  H  F  I  G         p.760

          .         .         .       | 14 .         .         .    g.40162
 CTTATGCAAATGATAGAGGGAATGAGACACGAAGAG | GGAGAATGCAGCTATGAATTGGAA    c.2340
 L  M  Q  M  I  E  G  M  R  H  E  E   | G  E  C  S  Y  E  L  E      p.780

          .         .         .         .         .         .       g.40222
 GTTGAATCTTATTTACAAATGGAAGATGTTACCTCAACATTTATTGCTCCCAGGAATGAA       c.2400
 V  E  S  Y  L  Q  M  E  D  V  T  S  T  F  I  A  P  R  N  E         p.800

          .         .         .         .         .         .       g.40282
 TCTAATAATCTTGCCAGTGACACCTTTATCACTCACAAGAAATCGTCATTTATAAAGAAC       c.2460
 S  N  N  L  A  S  D  T  F  I  T  H  K  K  S  S  F  I  K  N         p.820

          .         .         .         .         .         .       g.40342
 ATAAATCAAGGCAGTTCATCCTCAGTGATAGAATCTGATGAAGAATGTGCTGAAATTGTT       c.2520
 I  N  Q  G  S  S  S  S  V  I  E  S  D  E  E  C  A  E  I  V         p.840

          .         .         .         .         .         .       g.40402
 AAACAAACTCATATCAAACCTACTAAAATTGTTTCTTTAAAGAAAAAAGTGTCTAAAGAA       c.2580
 K  Q  T  H  I  K  P  T  K  I  V  S  L  K  K  K  V  S  K  E         p.860

          .         .         .         .         .         .       g.40462
 ATAAAAAAAGATCAGCTTAAAAAAGAAAATAATCACGGTATTATAGATTCTGTAGATAAT       c.2640
 I  K  K  D  Q  L  K  K  E  N  N  H  G  I  I  D  S  V  D  N         p.880

          .         .         .         .         .         .       g.40522
 GACAGAAATTCCACTGTTGAAAATATTTTTCAAGAAGACCTACCAAATGATAAAAGGACA       c.2700
 D  R  N  S  T  V  E  N  I  F  Q  E  D  L  P  N  D  K  R  T         p.900

          .         .         .         .         .         .       g.40582
 TCAGATACAGATGAAATTGCTGCCACATGTACTATTAATGAAAATGTTATTAAAGAACCG       c.2760
 S  D  T  D  E  I  A  A  T  C  T  I  N  E  N  V  I  K  E  P         p.920

          .         .         .         .         .         .       g.40642
 TGTGTGTTATTAACAGAGTGTCAGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAAT       c.2820
 C  V  L  L  T  E  C  Q  F  T  N  K  S  T  S  S  L  A  G  N         p.940

          .         .         .         .         .         .       g.40702
 GTTTTAGATTCTGGTTATAACAGTTTCAATGATGAAAAATCTGTTTCATCTAACTTATTT       c.2880
 V  L  D  S  G  Y  N  S  F  N  D  E  K  S  V  S  S  N  L  F         p.960

          .         .         .         .         .         .       g.40762
 CTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAGATGACCAATTTTATAATTGTCAC       c.2940
 L  P  F  E  E  E  L  Y  I  V  R  T  D  D  Q  F  Y  N  C  H         p.980

          .         .         .         .         .         .       g.40822
 TCATTGACAAAAGAGGTACTAGCTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCT       c.3000
 S  L  T  K  E  V  L  A  N  V  E  R  F  L  S  Y  S  P  P  P         p.1000

          .         .         .         .         .         .       g.40882
 CTCAGTGGACTCTCAGACTTGGAATATGAAATTGCTAAGGGTACTGCACTTGAGAATTTG       c.3060
 L  S  G  L  S  D  L  E  Y  E  I  A  K  G  T  A  L  E  N  L         p.1020

          .         .         .         .         .         .       g.40942
 CTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATAAATGCACCTGTTTGCTGTCACAT       c.3120
 L  F  L  P  C  A  E  H  L  R  S  D  K  C  T  C  L  L  S  H         p.1040

          .         .         .         .         .         .       g.41002
 TCAGCTGTGAATTCTCAACAGAATTTAGAATTGAATTCACTTAAATGTATAAATTATCCA       c.3180
 S  A  V  N  S  Q  Q  N  L  E  L  N  S  L  K  C  I  N  Y  P         p.1060

          .         .         .         .         .         .       g.41062
 TCTGAAAAAAGTTGCCTTTATGATATACCTAATGATAATATTTCTGATGAGCCAAGTCTC       c.3240
 S  E  K  S  C  L  Y  D  I  P  N  D  N  I  S  D  E  P  S  L         p.1080

          .         .         .         .         .         .       g.41122
 TGTGACTGTGATGTACATAAACATAATCAAAATGAAAATTTAGTACCTAACAATCGTGTT       c.3300
 C  D  C  D  V  H  K  H  N  Q  N  E  N  L  V  P  N  N  R  V         p.1100

          .         .         .         .         .         .       g.41182
 CAAATACACAGAAGCCCTGCACAGAATTTAGTTGGAGAGAACAATCATGATGTTGATAAC       c.3360
 Q  I  H  R  S  P  A  Q  N  L  V  G  E  N  N  H  D  V  D  N         p.1120

          .         .         .         .         .         .       g.41242
 AGTGACCTCCCAGTATTGTCCACTGATCAAGATGAAAGTTTGCTGTTATTTGAAGATGTT       c.3420
 S  D  L  P  V  L  S  T  D  Q  D  E  S  L  L  L  F  E  D  V         p.1140

          .         .         .         .         .         .       g.41302
 AATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGAACAGTAAAAGCGAATCTTTACCT       c.3480
 N  T  E  F  D  D  V  S  L  S  P  L  N  S  K  S  E  S  L  P         p.1160

          .         .         .         .         .         .       g.41362
 GTGTCAGACAAAACTGCTATTAGTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGAT       c.3540
 V  S  D  K  T  A  I  S  E  T  P  L  V  S  Q  F  L  I  S  D         p.1180

          .         .         .         .         .         .       g.41422
 GAACTTTTGTTGGACAATAATTCTGAACTCCAAGATCAAATCACCCGTGATGCTAATAGT       c.3600
 E  L  L  L  D  N  N  S  E  L  Q  D  Q  I  T  R  D  A  N  S         p.1200

          .         .         .         .         .         .       g.41482
 TTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAAAAGTGAAGAATCATGAGGATATT       c.3660
 F  K  S  R  D  Q  R  G  V  Q  E  E  K  V  K  N  H  E  D  I         p.1220

          .         .         .         .         .         .       g.41542
 TTTGATTGCTCTAGGGATTTATTTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGAT       c.3720
 F  D  C  S  R  D  L  F  S  V  T  F  D  L  G  F  C  S  P  D         p.1240

          .         .         .         .         .         .       g.41602
 TCTGATGATGAAATATTGGAACATACATCAGATAGCAATAGACCTCTAGATGATCTATAT       c.3780
 S  D  D  E  I  L  E  H  T  S  D  S  N  R  P  L  D  D  L  Y         p.1260

          .         .         .         .         .         .       g.41662
 GGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAAATTATGTTTCGAATCAAGCACTA       c.3840
 G  R  Y  L  E  I  K  E  I  S  D  A  N  Y  V  S  N  Q  A  L         p.1280

          .         .         .         .         .         .       g.41722
 ATACCAAGAGATCATAGTAAAAATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAA       c.3900
 I  P  R  D  H  S  K  N  F  T  S  G  T  V  I  I  P  S  N  E         p.1300

          .         .         .         .         .         .       g.41782
 GATATGCAGAATCCAAATTATGTACATTTGCCACTGAGTGCAGCAAAAAATGAAGAATTG       c.3960
 D  M  Q  N  P  N  Y  V  H  L  P  L  S  A  A  K  N  E  E  L         p.1320

          .         .         .         .         .         .       g.41842
 TTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGCAAAAAAAAGTTATGAGTACACCA       c.4020
 L  S  P  G  Y  S  Q  F  S  L  P  V  Q  K  K  V  M  S  T  P         p.1340

          .         .         .         .         .         .       g.41902
 CTCTCTAAATCAAACACATTGAACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACA       c.4080
 L  S  K  S  N  T  L  N  S  F  S  K  I  R  K  E  I  L  K  T         p.1360

          .         .         .         .         .         .       g.41962
 CCAGATTCTAGTAAGGAAAAAGTAAACCTACAAAGATTCAAAGAAGCATTGAATTCAACT       c.4140
 P  D  S  S  K  E  K  V  N  L  Q  R  F  K  E  A  L  N  S  T         p.1380

          .         .         .         .         .         .       g.42022
 TTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAAGCAGTGGTCCAATGTATCTGCAT       c.4200
 F  D  Y  S  E  F  S  L  E  K  S  K  S  S  G  P  M  Y  L  H         p.1400

          .         .   | 15     .         .         .         .    g.46535
 AAATCCTGTCATTCTGTTGAAG | ATGGACAATTATTAACAAGTAACGAAAGTGAAGATGAC    c.4260
 K  S  C  H  S  V  E  D |   G  Q  L  L  T  S  N  E  S  E  D  D      p.1420

          .         .         .         .         .        | 16.    g.46707
 GAGATTTTCCGAAGAAAAGTTAAAAGAGCAAAAGGAAATGTTTTAAACTCTCCTGAG | GAT    c.4320
 E  I  F  R  R  K  V  K  R  A  K  G  N  V  L  N  S  P  E   | D      p.1440

          .         .         .         .         .         .       g.46767
 CAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTGTCAAAAAGCGCAGATTTCCTATA       c.4380
 Q  K  N  S  E  V  D  S  P  L  H  A  V  K  K  R  R  F  P  I         p.1460

        | 17 .         .         .         .         .         .    g.48895
 AACAGA | TCAGAATTATCATCTAGTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAA    c.4440
 N  R   | S  E  L  S  S  S  D  E  S  E  N  F  P  K  P  C  S  Q      p.1480

          .         .         .         .         .         .       g.48955
 TTAGAAGACTTCAAGGTTTGTAACGGGAATGCCAGAAGAGGCATCAAAGTCCCAAAGAGA       c.4500
 L  E  D  F  K  V  C  N  G  N  A  R  R  G  I  K  V  P  K  R         p.1500

          .      | 18  .         .         .         .         .    g.50329
 CAGAGTCACTTAAAG | CATGTAGCTAGGAAGTTTTTAGATGATGAAGCAGAACTTTCTGAA    c.4560
 Q  S  H  L  K   | H  V  A  R  K  F  L  D  D  E  A  E  L  S  E      p.1520

          .         .         .         .         .         .       g.50389
 GAAGATGCAGAATATGTTTCATCAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCC       c.4620
 E  D  A  E  Y  V  S  S  D  E  N  D  E  S  E  N  E  Q  D  S         p.1540

          .         .         .         .         .   | 19     .    g.52856
 TCATTACTTGACTTTTTAAATGATGAAACTCAACTTTCACAGGCTATAAATG | ATTCTGAA    c.4680
 S  L  L  D  F  L  N  D  E  T  Q  L  S  Q  A  I  N  D |   S  E      p.1560

          .         .         .         .         .         .       g.52916
 ATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAATGATGAACAATAAGTACAAAATG       c.4740
 M  R  A  I  Y  M  K  S  L  R  S  P  M  M  N  N  K  Y  K  M         p.1580

          .         .         .          | 20        .         .    g.53890
 ATTCATAAGACACATAAAAACATAAACATTTTCTCGCAG | ATTCCTGAACAAGATGAAACC    c.4800
 I  H  K  T  H  K  N  I  N  I  F  S  Q   | I  P  E  Q  D  E  T      p.1600

          .         .         .         .         .         .       g.53950
 TATTTAGAGGATAGTTTTTGTGTTGATGAAGAGGAGTCTTGCAAAGGCCAATCAAGTGAA       c.4860
 Y  L  E  D  S  F  C  V  D  E  E  E  S  C  K  G  Q  S  S  E         p.1620

          .         .         .         .         .         .       g.54010
 GAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATGATTGCTTTGCAAATAGTAAAAAG       c.4920
 E  E  V  C  V  D  F  N  L  I  T  D  D  C  F  A  N  S  K  K         p.1640

          .         .         .         .         .         .       g.54070
 TATAAAACTCGACGTGCAGTAATGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCA       c.4980
 Y  K  T  R  R  A  V  M  L  K  E  M  M  E  Q  N  C  A  H  S         p.1660

          .         .         .         .         .         .       g.54130
 AAAAAGAAATTATCCAGAATTATTTTACCAGATGATTCAAGTGAGGAGGAGAACAATGTA       c.5040
 K  K  K  L  S  R  I  I  L  P  D  D  S  S  E  E  E  N  N  V         p.1680

          .         .         .         .         .         .       g.54190
 AATGATAAAAGAGAATCTAATATTGCGGTTAACCCAAGCACTGTTAAGAAGAACAAACAA       c.5100
 N  D  K  R  E  S  N  I  A  V  N  P  S  T  V  K  K  N  K  Q         p.1700

          .         .         .         .         .         .       g.54250
 CAGGACCATTGTTTAAATTCAGTGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCT       c.5160
 Q  D  H  C  L  N  S  V  P  S  G  S  S  A  Q  S  K  V  R  S         p.1720

          .         .         .         .         .         .       g.54310
 ACTCCAAGAGTTAATCCATTAGCAAAGCAGAGCAAACAGACATCGCTGAATTTAAAGGAT       c.5220
 T  P  R  V  N  P  L  A  K  Q  S  K  Q  T  S  L  N  L  K  D         p.1740

          .         .         .         .         .         .       g.54370
 ACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATCATAATGAAGTCCAGTCTACCACA       c.5280
 T  I  S  E  V  S  D  F  K  P  Q  N  H  N  E  V  Q  S  T  T         p.1760

          .         .         .         .         .         .       g.54430
 CCACCCTTCACTACTGTTGATTCACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAG       c.5340
 P  P  F  T  T  V  D  S  Q  K  D  C  R  K  F  P  V  P  Q  K         p.1780

  | 21       .         .         .         .         .         .    g.61299
  | GATGGTAGTGCTTTGGAGGATTCTAGCACTTCAGGGGCATCCTGTTCCAAGTCAAGACCA    c.5400
  | D  G  S  A  L  E  D  S  S  T  S  G  A  S  C  S  K  S  R  P      p.1800

          .         .         .         .         .         .       g.61359
 CATTTAGCTGGGACACATACTTCTCTTAGACTTCCGCAGGAAGGAAAAGGAACCTGTATT       c.5460
 H  L  A  G  T  H  T  S  L  R  L  P  Q  E  G  K  G  T  C  I         p.1820

          .         .         .         .         .         .       g.61419
 CTTGTAGGTGGTCATGAAATCACTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATT       c.5520
 L  V  G  G  H  E  I  T  S  G  L  E  V  I  S  S  L  R  A  I         p.1840

          .         .         .         .         .         .       g.61479
 CATGGGTTGCAAGTAGAAGTTTGTCCTCTTAATGGCTGTGATTACATCGTGAGTAATCGC       c.5580
 H  G  L  Q  V  E  V  C  P  L  N  G  C  D  Y  I  V  S  N  R         p.1860

          .         .         .         .         .         .       g.61539
 ATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAAATAGTGTCAATAAGAACAAGTTC       c.5640
 M  V  V  E  R  R  S  Q  S  E  M  L  N  S  V  N  K  N  K  F         p.1880

          .         .         .         .         .         .       g.61599
 ATTGAGCAGATCCAGCACCTGCAGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAG       c.5700
 I  E  Q  I  Q  H  L  Q  S  M  F  E  R  I  C  V  I  V  E  K         p.1900

          .       | 22 .         .         .         .         .    g.63755
 GACAGAGAAAAAACAG | GAGACACATCAAGGATGTTTAGGAGAACAAAGAGCTATGACAGC    c.5760
 D  R  E  K  T  G |   D  T  S  R  M  F  R  R  T  K  S  Y  D  S      p.1920

          .         .         .         .         .         .       g.63815
 CTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTCTTTTCAGTTCCTGCCAAGAAGAA       c.5820
 L  L  T  T  L  I  G  A  G  I  R  I  L  F  S  S  C  Q  E  E         p.1940

          .         .         .         .         .         .       g.63875
 ACCGCAGATTTGCTAAAGGAACTGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCAT       c.5880
 T  A  D  L  L  K  E  L  S  L  V  E  Q  R  K  N  V  G  I  H         p.1960

          .         .         .         .         .         .       g.63935
 GTTCCAACAGTGGTGAATAGTAATAAAAGTGAGGCACTCCAGTTTTATTTAAGTATTCCC       c.5940
 V  P  T  V  V  N  S  N  K  S  E  A  L  Q  F  Y  L  S  I  P         p.1980

          .         .         .         .         .         .       g.63995
 AATATAAGTTATATAACTGCATTAAATATGTGTCACCAGTTTTCATCTGTGAAAAGGATG       c.6000
 N  I  S  Y  I  T  A  L  N  M  C  H  Q  F  S  S  V  K  R  M         p.2000

          | 23         .         .         .         .         .    g.64989
 GCTAACAG | CTCACTTCAAGAAATCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAG    c.6060
 A  N  S  |  S  L  Q  E  I  S  M  Y  A  Q  V  T  H  Q  K  A  E      p.2020

          .         .         .         .         .         .       g.65049
 GAGATCTATAGATATATTCACTATGTATTTGACATACAAATGTTACCAAATGATCTTAAC       c.6120
 E  I  Y  R  Y  I  H  Y  V  F  D  I  Q  M  L  P  N  D  L  N         p.2040

          .         .                                               g.65076
 CAAGATAGACTGAAATCTGATATATAA                                        c.6147
 Q  D  R  L  K  S  D  I  X                                          p.2048

          .         .         .         .         .         .       g.65136
 tcaagctgctcaagatggggttttcaaagacctctcacaatattaaatgcacttcaataa       c.*60

          .         .         .         .         .         .       g.65196
 tcattgctgttttatgtttatttgtaaataagagaatattttatttaaatattttatatt       c.*120

          .         .         .         .         .         .       g.65256
 gtatacatttttatttatagattatagaaattattaaaaaagaaaaatctgatgttcagt       c.*180

          .         .         .         .         .         .       g.65316
 gatcattttgactagattataaaactaatttttcttattaaataaaacaaggtttattaa       c.*240

          .         .         .         .         .         .       g.65376
 aagtgttactaaggatagtttaagaaagtaaaagctaagctagagatatactttggaatg       c.*300

          .         .         .         .         .         .       g.65436
 tttcccaaaattaaagttgtactgttgtgataaatagtaaagttgacatgtctatgacta       c.*360

          .         .         .         .         .         .       g.65496
 cagccaacttgtcgattttccctatgtgtagatagtatacttttaagtgtactgattcta       c.*420

          .         .         .         .         .         .       g.65556
 aatacatgtacttggtaaggtgtgggtgatgggtgggttgtgagataaatgacccagtaa       c.*480

          .         .         .         .         .         .       g.65616
 ctaggaaagtagaaaacttaactgaatgtttatctgaccaaaggtgtgtcccagttaagt       c.*540

          .         .         .         .         .         .       g.65676
 actgtcaaatctattaatatgaactctgatatggtttggctgtgtccccaaccaaaatct       c.*600

          .         .         .         .         .         .       g.65736
 catcttgacttgtaatctgaattataatcccaatatattggggagggacctcctggaacg       c.*660

          .         .         .         .         .         .       g.65796
 tgattagctcatgggggcggttcccccatgctgttctagtgatagttctcagaggatctg       c.*720

          .         .         .         .         .         .       g.65856
 atggttttataagcttttcctctgttcactctgcagttctcttgcctactgccatgtgga       c.*780

          .         .         .         .         .         .       g.65916
 aaaggaaacgtttgcttcccctccaccatgattgtaagttcccgaggcctccccagccat       c.*840

          .         .         .         .                           g.65958
 gcaggactgtgagtcaattaaacatcttttccttataaatta                         c.*882

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10th nucleotide is indicated by a "." above the sequence. The Fanconi anemia, complementation group M protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift mutations, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.

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