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Over 45,000 nuclei from mouse Tibialis Anterior muscle were profiled across the lifespan using single-nucleus RNA-sequencing (10X Genomics)





Millay Lab

Nuclei are filtered for quality control and clustered based on cell identity and gene expression profile





Using Myoatlas, you are able to view expression of genes of interest across all populations of cells and myonuclei





If Myoatlas has assisted your research, please consider citing our manuscript:

Petrany, M.J., Swoboda, C.O., Sun, C. et al. Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers. Nat Commun 11, 6374 (2020). https://doi.org/10.1038/s41467-020-20063-w

Have questions? You can contact us at: Douglas.Millay@cchmc.org

Myoatlas is still under active development, check back for more data soon!

Select a timepoint and a gene of interest

For in-depth analysis on a single dataset

Single-nucleus RNA-seq of a TA muscle throughout the lifespan of a mouse

If you use these visualizations for your research, consider citing the original manuscript here

Millay Lab

Millay Lab

Compare gene expression in a single cell type across all time points

Visualize changes in gene expression across different time points

Millay Lab

Millay Lab

Select a timepoint and a gene of interest
Select which samples to include in visualizations

Distinct myofibre domains of the human myotendinous junction revealed by single-nucleus RNA sequencing

Anders Karlsen, Ching-Yan Chloe Yeung, Peter Schjerling, Linda Denz, Christian Hoegsbjerg, Jens R. Jakobsen, Michael R. Krogsgaard, Manuel Koch, Stefano Schiaffino, Michael Kjaer, Abigail L. Mackey

If you use these visualizations consider reading and citing the mansucript here