It may take a second, we have lots of data to explore!
Over 45,000 nuclei from mouse Tibialis Anterior muscle were profiled across the lifespan using single-nucleus RNA-sequencing (10X Genomics)
Nuclei are filtered for quality control and clustered based on cell identity and gene expression profile
Using Myoatlas, you are able to view expression of genes of interest across all populations of cells and myonuclei
If Myoatlas has assisted your research, please consider citing our manuscript:
Petrany, M.J., Swoboda, C.O., Sun, C. et al. Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers. Nat Commun 11, 6374 (2020). https://doi.org/10.1038/s41467-020-20063-w
Have questions? You can contact us at: Douglas.Millay@cchmc.org
Myoatlas is still under active development, check back for more data soon!
For in-depth analysis on a single dataset
Single-nucleus RNA-seq of a TA muscle throughout the lifespan of a mouse
If you use these visualizations for your research, consider citing the original manuscript
Visualize changes in gene expression across different time points