Fanconi anemia, complementation group F (FANCF) - coding DNA reference sequence
(used for mutation description)
(last modified May 1, 2014)
This file was created to facilitate the description of sequence variants in the FANCF gene based on a coding DNA reference sequence following the HGVS recommendations. The sequence was taken from NC_000011.9, covering FANCF transcript NM_022725.3.
Please note that introns are available by clicking on the exon numbers above the sequence.
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? p.0
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10th nucleotide is indicated by a "." above the sequence. The Fanconi anemia, complementation group F protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift mutations, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.
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