Exhaustive list - Orphan diseases network

This table contains the exhaustive list of each orphan disease and each related gene as rows, and the corresponding weakly connected component ID. You can explore any connected component by clicking on its ID, or start exploring by a specific node by clicking on its name.

**Orphan diseases and related genes interactive list**
Disease or gene name	Connected component ID
ABCA4	0
ABCC9	0
ACAN	0
ACTA2	0
ACTC1	0
ACTG1	0
ACTN2	0
ACVR2B	0
ADAM9	0
AHI1	0
AIPL1	0
ALS2	0
ANG	0
ANK2	0
APOE	0
APP	0
ARL13B	0
ARL6	0
ARVCF	0
ATP6V0A2	0
ATP7A	0
ATXN1	0
ATXN2	0
ATXN3	0
ATXN7	0
ATXN8	0
Achromatopsia	0
Alzheimer disease, familial	0
Amyotrophic lateral sclerosis	0
Anophthalmia - Microphthalmia, isolated	0
Arrhythmogenic right ventricular dysplasia	0
Atrial fibrillation, familial	0
Autosomal dominant Charcot-Marie-Tooth disease, type 2	0
Autosomal dominant cerebellar ataxia	0
BAZ1B	0
BBS1	0
BBS10	0
BBS12	0
BBS2	0
BBS4	0
BBS5	0
BBS7	0
BBS9	0
BCKDHA	0
BCKDHB	0
BCL7B	0
BCR	0
BCS1L	0
BFSP1	0
BFSP2	0
BSND	0
Bardet-Biedl syndrome	0
Bartter syndrome	0
C14orf104	0
C1QTNF5	0
C20orf7	0
C8orf38	0
CA4	0
CABP4	0
CACNA1A	0
CACNA1C	0
CACNA1F	0
CACNA2D4	0
CAV3	0
CBFB	0
CC2D2A	0
CCDC50	0
CDH23	0
CEP290	0
CERKL	0
CFC1	0
CFC1B	0
CHMP2B	0
CHMP4B	0
CHST3	0
CLCNKA	0
CLCNKB	0
CLDN14	0
CLIP2	0
CLRN1	0
CNGA1	0
CNGA3	0
CNGB1	0
CNGB3	0
COCH	0
COL11A1	0
COL11A2	0
COL17A1	0
COL2A1	0
COL7A1	0
COL9A1	0
COL9A2	0
COL9A3	0
COMP	0
COX10	0
COX15	0
CRB1	0
CRX	0
CRYAA	0
CRYAB	0
CRYBA1	0
CRYBA4	0
CRYBB1	0
CRYBB2	0
CRYBB3	0
CRYGC	0
CRYGD	0
CRYM	0
CSRP3	0
Cardiomyopathy, familial dilated	0
Cardiomyopathy, hypertrophic, primary or idiopathic	0
Cataract, cerulean	0
Cataract, posterior polar	0
Cataract, pulverulent	0
Cataract, zonular	0
Charcot-Marie-Tooth disease, type 1	0
Coenzyme Q cytochrome c reductase deficiency	0
Colon cancer, familial nonpolyposis	0
Cone rod dystrophy	0
Conotruncal heart malformations	0
Cutis laxa	0
DBT	0
DDR2	0
DES	0
DFNA5	0
DFNB31	0
DFNB59	0
DIAPH1	0
DLAT	0
DLD	0
DMD	0
DNAH11	0
DNAH5	0
DNAI1	0
DNAI2	0
DNAJC30	0
DSC2	0
DSG2	0
DSP	0
Deafness, autosomal dominant, nonsyndromic, sensorineural, type DFNA	0
Deafness, autosomal recessive, nonsyndromic, sensorineural, type DFNB	0
Dejerine-Sottas syndrome	0
EFEMP2	0
EGR2	0
EIF4H	0
ELN	0
EMD	0
EPHA2	0
ESPN	0
ESRRB	0
ETV6	0
EYA4	0
Emery-Dreifuss muscular dystrophy	0
Epidermolysis bullosa, epidermolytic	0
Epidermolysis bullosa, generalized atrophic benign	0
Epidermolysis bullosa, junctional	0
Epidermolysis bullosa, junctional, non-Herlitz type	0
Epiphyseal dysplasia multiple	0
FBLN5	0
FBN1	0
FGF14	0
FHL2	0
FIG4	0
FKBP6	0
FKRP	0
FKTN	0
FLT3	0
FSCN2	0
FUS	0
Fatal infantile cytochrome C oxidase deficiency	0
Frontotemporal dementia	0
GARS	0
GATA4	0
GDAP1	0
GDF1	0
GJA1	0
GJA3	0
GJA8	0
GJB2	0
GJB3	0
GJB6	0
GLIS2	0
GNAT1	0
GNAT2	0
GPR98	0
GRHL2	0
GRM6	0
GRN	0
GTF2I	0
GTF2IRD1	0
GTPBP3	0
GUCA1A	0
GUCA1B	0
GUCY2D	0
HGF	0
HMCN1	0
HSF4	0
HSPB1	0
HSPB8	0
HTRA1	0
Heterotaxia	0
IDH3B	0
IFRD1	0
IMPDH1	0
INPP5E	0
INVS	0
IQCB1	0
ITGA6	0
ITGB4	0
Interauricular communication	0
JAG1	0
JUP	0
Joubert syndrome	0
KCNA5	0
KCNE1	0
KCNE2	0
KCNH2	0
KCNJ1	0
KCNJ10	0
KCNJ2	0
KCNQ1	0
KCNQ4	0
KCNV2	0
KIF1B	0
KLHL7	0
KRT14	0
KRT5	0
LAMA3	0
LAMB3	0
LAMC2	0
LARGE	0
LAT2	0
LCA5	0
LDB3	0
LEFTY2	0
LHFPL5	0
LIM2	0
LIMK1	0
LITAF	0
LMNA	0
LOX	0
LRAT	0
LRPPRC	0
LRTOMT	0
Leber amaurosis, congenital	0
Leber hereditary optic neuropathy	0
Leigh syndrome	0
Leucinosis	0
Leukemia, myeloid, acute	0
Long QT syndrome, familial	0
MAF	0
MAPK1	0
MAPT	0
MARVELD2	0
MATN3	0
MED13L	0
MELAS syndrome	0
MERTK	0
MFN2	0
MFRP	0
MIP	0
MKKS	0
MKS1	0
MLH1	0
MLH3	0
MLXIPL	0
MMP13	0
MPZ	0
MSH2	0
MSH6	0
MT-ATP6	0
MT-ATP8	0
MT-CO1	0
MT-CO3	0
MT-CYB	0
MT-ND1	0
MT-ND2	0
MT-ND3	0
MT-ND4	0
MT-ND4L	0
MT-ND5	0
MT-ND6	0
MYBPC3	0
MYH11	0
MYH14	0
MYH6	0
MYH7	0
MYH9	0
MYL2	0
MYL3	0
MYLK2	0
MYO15A	0
MYO1A	0
MYO3A	0
MYO6	0
MYO7A	0
Macular degeneration, age-related	0
Meckel syndrome	0
Medullary cystic kidney disease, autosomal recessive	0
Monosomy 22q11	0
NADH-CoQ reductase deficiency	0
NDUFA1	0
NDUFA11	0
NDUFAF2	0
NDUFAF3	0
NDUFAF4	0
NDUFS1	0
NDUFS2	0
NDUFS3	0
NDUFS4	0
NDUFS6	0
NDUFS7	0
NDUFS8	0
NDUFV1	0
NDUFV2	0
NEFH	0
NEFL	0
NEK8	0
NKX2-5	0
NPHP1	0
NPHP3	0
NPHP4	0
NPPA	0
NR1H3	0
NR2E3	0
NRL	0
NUP155	0
NYX	0
Night blindness, stationary, congenital	0
Non-syndromic congenital cataract	0
Nonsyndromic genetic deafness	0
OFD1	0
OLR1	0
OTOA	0
OTOF	0
OTX2	0
PAPSS2	0
PC	0
PCDH15	0
PDE6A	0
PDE6B	0
PDE6C	0
PDE6H	0
PDGFRL	0
PDHA1	0
PDHB	0
PDHX	0
PIK3CA	0
PITX3	0
PKP2	0
PLEC1	0
PLEKHG5	0
PLN	0
PMP22	0
PMS1	0
PMS2	0
POMGNT1	0
POMT1	0
POMT2	0
POU3F4	0
POU4F3	0
PPP2R2B	0
PRCD	0
PRKAG2	0
PRKCG	0
PROM1	0
PRPF3	0
PRPF31	0
PRPF8	0
PRPH	0
PRPH2	0
PRX	0
PSEN1	0
PSEN2	0
Primary ciliary dyskinesia	0
Progressive cone dystrophy	0
Pyruvate dehydrogenase deficiency	0
RAB7A	0
RAX	0
RAX2	0
RD3	0
RDH12	0
RDX	0
RFC2	0
RGR	0
RHO	0
RIMS1	0
RLBP1	0
ROM1	0
RP1	0
RP2	0
RP9	0
RPE65	0
RPGR	0
RPGRIP1	0
RPGRIP1L	0
RSPH4A	0
RSPH9	0
RYR2	0
Retinitis pigmentosa	0
SCN4B	0
SCN5A	0
SCO1	0
SCO2	0
SDHA	0
SEMA4A	0
SETX	0
SGCD	0
SLC12A1	0
SLC17A8	0
SLC26A2	0
SLC26A4	0
SLC26A5	0
SOD1	0
SPATA7	0
SPTBN2	0
STRC	0
SURF1	0
SYNE1	0
SYNE2	0
Senior-Loken syndrome	0
Situs ambiguus	0
Spondyloepimetaphyseal dysplasia	0
Spondyloepiphyseal dysplasia	0
Stickler syndrome	0
TACO1	0
TARDBP	0
TAZ	0
TBL2	0
TBP	0
TBX1	0
TCAP	0
TECTA	0
TFB1M	0
TGFB3	0
TGFBR1	0
TGFBR2	0
TMC1	0
TMEM43	0
TMEM67	0
TMIE	0
TMPO	0
TMPRSS3	0
TNNC1	0
TNNI3	0
TNNT2	0
TOPORS	0
TPM1	0
TRAPPC2	0
TRIM32	0
TRIOBP	0
TRMU	0
TTC8	0
TTN	0
TULP1	0
TXNDC3	0
Tetralogy of Fallot	0
Thoracic aortic aneurysm, familial form	0
Transposition of the great arteries	0
Transposition of the great arteries, right	0
UFD1L	0
UQCRB	0
UQCRQ	0
USH1C	0
USH1G	0
USH2A	0
Usher syndrome	0
VAPB	0
VCL	0
VSX2	0
WBSCR16	0
WBSCR22	0
WBSCR27	0
WFS1	0
WISP3	0
Walker-Warburg syndrome	0
Williams syndrome	0
ZFPM2	0
ZIC3	0
DIRC1	1
DIRC2	1
EGLN1	1
EPAS1	1
EPOR	1
FHIT	1
HIF1A	1
HSPBAP1	1
OGG1	1
Primary familial polycythemia	1
RNF139	1
Renal cell carcinoma, familial	1
VHL	1
Adrenoleukodystrophy, neonatal	2
HSD17B4	2
PEX1	2
PEX10	2
PEX12	2
PEX13	2
PEX14	2
PEX16	2
PEX19	2
PEX26	2
PEX3	2
PEX5	2
PEX6	2
PXMP3	2
Refsum disease, infantile form	2
Zellweger syndrome	2
ACSL4	3
AGTR2	3
ARHGEF6	3
ARX	3
Atypical Rett syndrome	3
BRWD3	3
CC2D1A	3
CDH15	3
CDKL5	3
CRBN	3
DLG3	3
FG syndrome	3
FLNA	3
FOXG1	3
FTSJ1	3
GDI1	3
IL1RAPL1	3
KIRREL3	3
MECP2	3
MED12	3
NTNG1	3
PAK3	3
PRSS12	3
RPS6KA3	3
Rare intellectual deficit without developmental anomaly	3
SYNGAP1	3
TSPAN7	3
TUSC3	3
UPF3B	3
ZNF41	3
ZNF674	3
ZNF81	3
ACE	4
AGT	4
AGTR1	4
REN	4
Renal tubular dysgenesis	4
ACTA1	5
CFL2	5
MYH3	5
Mild nemaline myopathy	5
NEB	5
Nemaline myopathy	5
Sheldon-Hall syndrome	5
TNNI2	5
TNNT1	5
TNNT3	5
TPM2	5
TPM3	5
Beckwith-Wiedemann syndrome	6
CDKN1C	6
COPG2	6
CPA4	6
GRB10	6
IGF2	6
MEST	6
NSD1	6
SLC22A18	6
Silver-Russell syndrome	6
ANK1	7
EPB42	7
SLC4A1	7
SPTA1	7
SPTB	7
Spherocytosis hereditary	7
BMP4	8
Cleft lip with or without cleft palate	8
FBXW4	8
IRF6	8
PVRL1	8
SHFM1	8
SUMO1	8
Split hand - split foot	8
TGFA	8
TP63	8
WNT10B	8
HLA-DRB1	9
LOC100294161	9
LOC100294189	9
LOC100294468	9
Sarcoidosis	9
CLINT1	10
DISC1	10
FXYD6	10
PRODH	10
RGS4	10
Schizophrenia	10
C10orf2	11
DGUOK	11
MPV17	11
Mitochondrial DNA depletion syndrome	11
POLG	11
POLG2	11
Progressive external ophthalmoplegia	11
SLC25A4	11
TK2	11
TYMP	11
ASPM	12
BARD1	12
BRCA1	12
BRCA2	12
BRIP1	12
Breast cancer, familial	12
CDK5RAP2	12
CENPJ	12
CHEK2	12
CYP11A1	12
CYP11B1	12
CYP17A1	12
CYP21A2	12
Congenital adrenal hyperplasia	12
ELAC2	12
EPHB2	12
FANCA	12
FANCB	12
FANCC	12
FANCD2	12
FANCE	12
FANCF	12
FANCG	12
FANCI	12
FANCL	12
FANCM	12
Fanconi anemia	12
HLF	12
HNF1B	12
HSD17B3	12
HSD3B2	12
ING1	12
ING3	12
LMO1	12
LYL1	12
Leukemia, lymphoblastic, acute	12
MCPH1	12
MLL	12
MXI1	12
Microcephaly, isolated congenital	12
PALB2	12
PBX1	12
PDGFRA	12
PTEN	12
Prostate cancer, familial	12
RAD51	12
RNASEL	12
SRD5A2	12
STIL	12
Squamous cell carcinoma of head and neck	12
TAL1	12
TAL2	12
TCF3	12
TLX1	12
TNFRSF10B	12
BMP15	13
DIAPH2	13
FMR1	13
FOXL2	13
FSHR	13
NOBOX	13
POF1B	13
Premature ovarian failure	13
MAGEL2	14
NDN	14
OCA2	14
Oculocutaneous albinism	14
Prader-Willi syndrome	14
SLC45A2	14
SNRPN	14
TYR	14
TYRP1	14
CSF2RA	15
CSF2RB	15
Pulmonary alveolar proteinosis	15
SFTPB	15
SFTPC	15
NR3C2	16
Pseudohypoaldosteronism, type 1	16
SCNN1A	16
SCNN1B	16
SCNN1G	16
COFS syndrome	17
DDB2	17
ERCC1	17
ERCC2	17
ERCC3	17
ERCC4	17
ERCC5	17
ERCC6	17
POLH	17
XPA	17
XPC	17
Xeroderma pigmentosum	17
ALK	18
ASCL1	18
BDNF	18
CCDC6	18
ECE1	18
EDN3	18
EDNRB	18
ERC1	18
GDNF	18
GOLGA5	18
Hirschsprung disease	18
L1CAM	18
MYCN	18
NCOA4	18
NME1	18
NRTN	18
Neuroblastoma	18
Ondine syndrome	18
PCM1	18
PHOX2B	18
RET	18
TFG	18
TPR	18
TRIM24	18
TRIM27	18
TRIM33	18
Thyroid carcinoma, papillary or follicular	18
SS18	19
SSX1	19
SSX2	19
SSX2B	19
SSX2IP	19
Synovialosarcoma	19
Encephalopathy due to sulfite oxidase deficiency	20
GLRA1	20
GLRB	20
GPHN	20
Hyperekplexia, hereditary	20
MOCOS	20
MOCS1	20
MOCS2	20
SLC6A5	20
SUOX	20
XDH	20
Xanthinuria	20
CYP27B1	21
CYP2R1	21
Calcinosis, tumoral	21
DMP1	21
FGF23	21
GALNT3	21
KL	21
PHEX	21
SAMD9	21
SLC34A3	21
VDR	21
Vitamin D resistant rickets	21
Leukemia, promyelocytic, acute	22
NPM1	22
PML	22
RARA	22
ZBTB16	22
CLN3	23
CLN5	23
CLN6	23
CLN8	23
CTSD	23
Late infantile neuronal ceroid lipofuscinosis	23
MFSD8	23
Neuronal ceroid lipofuscinosis	23
PPT1	23
TPP1	23
CHD7	24
FGF8	24
FGFR1	24
GNRH1	24
GNRHR	24
KAL1	24
KISS1R	24
Kallmann syndrome	24
NELF	24
Normosmic congenital hypogonadotropic hypogonadism	24
PROK2	24
PROKR2	24
TAC3	24
TACR3	24
ABCC8	25
CEL	25
Diabetes mellitus, neonatal	25
Diabetes mellitus, neonatal, permanent	25
GCK	25
HADH	25
HNF1A	25
HNF4A	25
INS	25
INSR	25
KCNJ11	25
KLF11	25
MODY syndrome	25
NEUROD1	25
PAX4	25
PDX1	25
PTF1A	25
Persistent hyperinsulinemic hypoglycemia of infancy	25
SLC16A1	25
ZFP57	25
CHAT	26
CHRNA1	26
CHRNB1	26
CHRND	26
CHRNE	26
CHRNG	26
COLQ	26
Congenital myasthenic syndromes	26
DOK7	26
LAMB2	26
MUSK	26
Multiple pterygium syndrome, lethal form	26
Postsynaptic congenital myasthenic syndromes	26
RAPSN	26
SCN4A	26
GNS	27
HGSNAT	27
Mucopolysaccharidosis type 3	27
NAGLU	27
SGSH	27
KRT81	28
KRT83	28
KRT86	28
LOC100293351	28
Monilethrix	28
BCL10	29
BIRC3	29
FOXP1	29
MALT lymphoma	29
MALT1	29
APOA5	30
APOC2	30
GPIHBP1	30
LIPI	30
LPL	30
Major hypertriglyceridemia	30
IFNGR1	31
IFNGR2	31
IL12B	31
IL12RB1	31
Mendelian susceptibility to atypical mycobacteria	31
STAT1	31
APC	32
CTNNB1	32
Medulloblastoma	32
PTCH2	32
SUFU	32
BRAF	33
CDKN2A	33
Cardiofaciocutaneous syndrome	33
DMBT1	33
EGFR	33
GLI1	33
GLTSCR1	33
GLTSCR2	33
Glioblastoma	33
KRAS	33
LRRN2	33
MANF	33
MAP2K1	33
MAP2K2	33
Noonan syndrome	33
PTPN11	33
Pancreatic carcinoma, familial	33
RAF1	33
SMAD4	33
SOS1	33
TP53	33
YEATS4	33
MTHFD1	34
MTHFR	34
MTR	34
Neural tube defect	34
T	34
VANGL1	34
HESX1	35
LHX3	35
Nonacquired combined pituitary hormone deficiency	35
POU1F1	35
PROP1	35
GJC2	36
HSPD1	36
PLP1	36
Pelizaeus-Merzbacher disease	36
SLC16A2	36
ATP13A2	37
GIGYF2	37
HTRA2	37
LRRK2	37
NR4A2	37
PACRG	37
PARK2	37
PARK7	37
PINK1	37
Parkinson disease, genetic type	37
SNCA	37
UCHL1	37
CYP1B1	38
FOXC1	38
Glaucoma, congenital	38
Glaucoma, hereditary	38
HDAC9	38
LTBP2	38
MYOC	38
OPTN	38
PAX6	38
PITX2	38
Peters anomaly	38
TGFB2	38
WDR36	38
Pontocerebellar hypoplasia	39
RARS2	39
TSEN2	39
TSEN34	39
TSEN54	39
GPR56	40
NHEJ1	40
Polymicrogyria	40
SRPX2	40
TUBB2B	40
ALAS2	41
FECH	41
HAMP	41
HFE	41
HFE2	41
Hemochromatosis	41
Porphyria	41
TFR2	41
UROD	41
UROS	41
DCLRE1C	42
LIG4	42
Omenn syndrome	42
RAG1	42
RAG2	42
KRT16	43
KRT17	43
KRT6A	43
KRT6B	43
Pachyonychia congenita	43
COL1A1	44
COL1A2	44
COL3A1	44
COL5A1	44
COL5A2	44
CRTAP	44
Classic Ehlers-Danlos syndrome	44
LEPRE1	44
Osteogenesis imperfecta	44
TNXB	44
DKC1	45
Dyskeratosis congenita	45
IFNG	45
Idiopathic aplastic anemia	45
NHP2	45
NOP10	45
PRF1	45
SBDS	45
TERT	45
TINF2	45
Crohn disease	46
IL10	46
IL23R	46
NOD2	46
SLC22A4	46
Crigler-Najjar syndrome	47
Gilbert syndrome	47
Hyperbilirubinemia transient familial neonatal	47
UGT1A1	47
UGT1A10	47
UGT1A3	47
UGT1A4	47
UGT1A5	47
UGT1A6	47
UGT1A7	47
UGT1A8	47
UGT1A9	47
GABRD	48
GABRG2	48
Generalized epilepsy with febrile seizures-plus context	48
SCN1A	48
SCN1B	48
SCN2A	48
ERG	49
ETV1	49
EWSR1	49
Ewing sarcoma	49
FLI1	49
NR4A3	49
ABCA12	50
ABHD5	50
ALOX12B	50
ALOXE3	50
CYP4F22	50
Erythroderma, congenital ichthyosiform, nonbullous	50
Ichthyosis, lamellar	50
KRT1	50
KRT10	50
TGM1	50
FOXH1	51
GLI2	51
Holoprosencephaly	51
PTCH1	51
SHH	51
SIX3	51
TDGF1	51
TGIF1	51
ZIC2	51
ABCG5	52
ABCG8	52
APOB	52
Hypercholesterolemia, familial	52
LDLR	52
LDLRAP1	52
PCSK9	52
SREBF2	52
Hereditary pheochromocytoma-paraganglioma syndrome	53
SDHAF2	53
SDHB	53
SDHC	53
SDHD	53
BLOC1S3	54
DTNBP1	54
HPS1	54
HPS3	54
HPS4	54
HPS5	54
HPS6	54
Hermansky-Pudlak syndrome	54
CYBA	55
CYBB	55
Granulomatous disease, chronic	55
NCF1	55
NCF2	55
NCF4	55
CFTR	56
CTRC	56
Hereditary chronic pancreatitis	56
PRSS1	56
PRSS2	56
REG1A	56
SPINK1	56
ETFA	57
ETFB	57
ETFDH	57
GCDH	57
Glutaryl-CoA dehydrogenase deficiency	57
DHH	58
DMRT1	58
DMRT2	58
Gonadal dysgenesis, XY female type	58
NR0B1	58
NR5A1	58
SRY	58
ABCD1	59
AMN	59
CUBN	59
DHFR	59
Graesbeck-Imerslund disease	59
Atypical hemolytic uremic syndrome	60
C2	60
C3	60
C4A	60
C4B	60
C5	60
C6	60
C7	60
C8A	60
C8B	60
C8G	60
C9	60
CD46	60
CFH	60
CFI	60
Immunodeficiency with a complement cascade protein anomaly	60
SERPING1	60
CACNB4	61
EFHC1	61
GABRA1	61
JRK	61
Juvenile myoclonic epilepsy	61
KCNQ3	61
CIITA	62
Immunodeficiency by defective expression of HLA class 2	62
RFX5	62
RFXANK	62
RFXAP	62
TAP2	62
Iminoglycinuria	63
SLC36A2	63
SLC6A18	63
SLC6A19	63
SLC6A20	63
DUOX2	64
DUOXA2	64
Hypothyroidism, congenital	64
IYD	64
NKX2-1	64
PAX8	64
SLC5A5	64
TPO	64
TRH	64
TSHB	64
TSHR	64
AICDA	65
CD40	65
Hyper-IgM syndrome	65
IKBKG	65
UNG	65
AXIN2	66
EDA	66
Hypodontia	66
MSX1	66
PAX9	66
WNT10A	66
AUTS2	67
Autism	67
EN2	67
GABRB3	67
MET	67
NLGN3	67
NLGN4X	67
NRXN1	67
RPL10	67
Autosomal dominant centronuclear myopathy	68
BIN1	68
Centronuclear myopathy	68
DNM2	68
MAMLD1	68
MTM1	68
MTMR14	68
MYF6	68
RYR1	68
Autoimmune lymphoproliferative syndrome	69
CASP10	69
CASP8	69
FAS	69
FASLG	69
Autosomal recessive spondylocostal dysostosis	70
DLL3	70
HES7	70
LFNG	70
MESP2	70
Autosomal recessive malignant osteopetrosis	71
CLCN7	71
OSTM1	71
TCIRG1	71
TNFRSF11A	71
TNFSF11	71
AKR1D1	72
AMACR	72
Bile acid synthesis defect with cholestasis and malabsorption	72
CYP7B1	72
HSD3B7	72
Blackfan-Diamond disease	73
RPL11	73
RPL35A	73
RPL5	73
RPS17	73
RPS19	73
RPS24	73
RPS7	73
CACH syndrome	74
Congenital or early infantile CACH syndrome	74
Cree leukoencephalopathy	74
EIF2B1	74
EIF2B2	74
EIF2B3	74
EIF2B4	74
EIF2B5	74
Juvenile or adult CACH syndrome	74
Late infantile CACH syndrome	74
Ovarioleukodystrophy	74
BMPR1B	75
Brachydactyly	75
GDF5	75
HOXD13	75
IHH	75
ROR2	75
Chromosome Y deletion	76
DAZ1	76
DAZ2	76
DAZ3	76
DAZ4	76
DDX3Y	76
RBMY1A1	76
USP9Y	76
CHST6	77
COL8A2	77
Corneal dystrophy	77
DCN	77
KRT12	77
KRT3	77
PIKFYVE	77
SLC4A11	77
TACSTD2	77
TGFBI	77
VSX1	77
ZEB1	77
APOA1	78
APOA2	78
Amyloid nephropathy, familial	78
Amyloidosis	78
CST3	78
FGA	78
GSN	78
IGHG1	78
LYZ	78
TTR	78
AMELX	79
Amelogenesis imperfecta	79
DLX3	79
ENAM	79
FAM83H	79
KLK4	79
MMP20	79
Aicardi-Goutieres syndrome	80
RNASEH2A	80
RNASEH2B	80
RNASEH2C	80
SAMHD1	80
TREX1	80

The exploration is done with the Adobe Flash Web application GexfWalker. (Hint: find a specific orphan disease or related gene by searching it with the search feature of your web browser)

Orphan diseases network

4. Bipartite network - All diseases connected to more than 3 genes