Publications

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2022

1. ‣ Gautam Y, Johansson E, Mersha TB (2022). Multi-Omics Profiling Approach to Asthma: An Evolving Paradigm. J Pers Med. 2022 Jan 7; 12(1):66. PMCID: PMC8778153.
   

2. ‣ Kang M., Ko E., Mersha TB (2022). A roadmap for multi-omics data integration using deep learning.Briefings in Bioinformatics. Volume 23, Issue 1. January 2022.
   

3. ‣ Gautam Y, Caldwell J, Kottyan L, Chehade M, Dellon ES, Rothenberg ME, Mersha TB (2022). Genome-wide admixture and association analysis identifies African ancestry specific risk loci of eosinophilic esophagitis in African American. J Allergy Clin Immunol. 2022 Nov 15:S0091-6749(22)01474-9. Epub ahead of print. PMID: 36400179.
   

4. ‣ Correa-Agudelo E, Ding L, Beck AF, Brokamp C, Altaye M, Kahn RS, Mersha TB (2022). Understanding racial disparities in childhood asthma using individual- and neighborhood-level risk factors. Journal of Allergy and Clinical Immunology. Volume 150, Issue 6.
   

5. ‣ Cao X, Ding L, Mersha TB (2022). Development and validation of an RNA-seq-based transcriptomic risk score for asthma. Sci Rep. 2022 May 23;12(1):8643. PMID: 35606385; PMCID: PMC9126925.
   

6. ‣ Gautam Y, Mersha TB (2022). Leveraging genetic ancestry to study severe asthma exacerbations in an admixed population. Thorax. 2022 Nov 18:thorax-2022-219459. Epub ahead of print. PMID: 36400457.
   

7. ‣ Mendy A, Burcham S, Merianos AL, Mersha TB, Mahabee-Gittens EM, Chen A, Yolton K (2022). Urinary volatile organic compound metabolites and reduced lung function in U.S. adults. Respir Med. 2022 Dec;205:107053. Epub 2022 Nov 10. PMID: 36399896.
   

8. ‣ Parikh MN, Brokamp C, Rasnick E, Ding L, Mersha TB, Bowers K, Folger AT (2022). Epigenome-wide association of neonatal methylation and trimester-specific prenatal PM2.5 exposure. Environ Epidemiol. 2022 Oct 3;6(5):e227. PMID: 36249271; PMCID: PMC9556110.
   

9. ‣ Mendy A, Merianos AL, Mersha TB, Mahabee-Gittens EM (2022). Blood volatile organic compounds associated with non-reversible and reversible airflow obstruction in US adults. Eur Respir J. 2022 Nov 17;60(5):2201185. PMID: 36202413.
   

10. ‣ Pennington J, Rasnick E, Martin LJ, Biagini JM, Mersha TB, Parsons A, Khurana Hershey GK, Ryan P, Brokamp C (2022). Racial Fairness in Precision Medicine: Pediatric Asthma Prediction Algorithms. Am J Health Promot. 2022 Aug 16:8901171221121639. Epub ahead of print. PMID: 35973209.
    

11. ‣ Roman YM, McClish D, Price ET, Sabo RT, Woodward OM, Mersha TB, Shah N, Armada A, Terkeltaub R (2022). Cardiometabolic genomics and pharmacogenomics investigations in Filipino Americans: Steps towards precision health and reducing health disparities. Am Heart J Plus. 2022 Mar;15:100136. Epub 2022 Apr 27. PMID: 35647570; PMCID: PMC9139029.
    

12. ‣ Ghosh D, Mersha TB (2022). Publicly available cytokine data: Limitations and opportunities. J Allergy Clin Immunol. 2022 Nov;150(5):1053-1056. Epub 2022 Aug 13. PMID: 35970308.
    

13. ‣ Namjou B, Lape M, Malolepsza E, DeVore SB, Weirauch MT, Dikilitas O, Jarvik GP, Kiryluk K, Kullo IJ, Liu C, Luo Y, Satterfield BA, Smoller JW, Walunas TL, Connolly J, Sleiman P, Mersha TB, Mentch FD, Hakonarson H, Prows CA, Biagini JM, Khurana Hershey GK, Martin LJ, Kottyan L; eMERGE Network (2022). Multiancestral polygenic risk score for pediatric asthma. J Allergy Clin Immunol. 2022 Nov;150(5):1086-1096. Epub 2022 May 18. PMID: 35595084; PMCID: PMC9643615.
    

14. ‣ Mendy A, Mersha TB (2022). Comorbidities in childhood-onset and adult-onset asthma. Ann Allergy Asthma Immunol. 2022 Sep;129(3):327-334. Epub 2022 May 18. PMID: 35595004.
    

15. ‣ Dadi AF, Mersha TB (2022). WHO's surveillance system for attacks on health care is failing Ethiopia. Lancet. 2022 Mar 26;399(10331):1225-1226. Erratum in: Lancet. 2022 Apr 23;399(10335):1606. PMID: 35339222.
    

16. ‣ Enquobahrie DA, Tekola-Ayele F, Mersha TB (2022). Editorial: Genetic and Epigenetic Insights Into the Developmental Origins of Health and Disease. Front Genet. 2022 Feb 4;12:814126. PMID: 35186017; PMCID: PMC8856002.
    

2021

17. ‣ Mersha TB, Qin K, Beck AF, Ding L, Huang B, Kahn RS (2021). Genetic ancestry differences in pediatric asthma readmission are mediated by socioenvironmental factors. J Allergy Clin Immunol. 148(5):1210-1218. PMID: 34217757 (Editor's Choice JACI Nov 2021 volume and Featured article @AAAAI website).
    

18. ‣ Stevens ML, Mersha TB, Zhang Z, Kothari A, Hershey GKK (2021). Skin depletion of Kif3a resembles the pediatric atopic dermatitis transcriptome profile. Human Molecular Genetics, ddab342 (In press).
    

19. ‣ Chidambaran V, Mersha TB (2021). A step towards understanding disparities: linking race, ancestry, epigenetics and pain. Epigenomics. 13(22):1791-1796. PMID: 34617457.
    

20. ‣ Proper SP, Azouz NP, Mersha TB (2021). Achieving Precision Medicine in Allergic Disease: Progress and Challenges. Front Immunol. 12:720746. PMID: 34484229.
    

21. ‣ Mendy A, Wu X, Keller JL, Fassler CS, Apewokin S, Mersha TB, Xie C, Pinney SM (2021). Air pollution and the pandemic: Long-term PM2.5 exposure and disease severity in COVID-19 patients. Respirology. 2021 Aug 30. doi: 10.1111/resp.14140. PMID: 34459069.
    

22. ‣ Beyene J, Harrar SW, Altaye M, Astatkie T, Awoke T, Shkedy Z and Mersha TB (2021). A Roadmap for Building Data Science Capacity for Health Discovery and Innovation in Africa. Front. Public Health 9:710961. PMID: 34708013.
    

23. ‣ Hardy DS, Racette SB, Garvin JT, Gebrekristos HT, Mersha TB (2021). Ancestry specific associations of a genetic risk score, dietary patterns and metabolic syndrome: a longitudinal ARIC study. BMC Med Genomics 14(1):118. PMID: 33933074.
    

24. ‣ (2021). .
    

25. ‣ Johansson E, Mersha TB (2021). Genetics of food allergy. Immunol Allergy Clin North Am 41(2):301-319. PMID: 33863485.
    

26. ‣ Jones DE, Park JS, Gamby K, Bigelow TM, Mersha TB, Folger AT (2021). Mental health epigenetics: A primer with implications for counselors. The Professional Counselor, 1(11), 116–135.
    

27. ‣ Brandt EB, Mersha TB (2021). Environmental Determinants of Coronavirus Disease 2019 (COVID-19). Curr Allergy Asthma Rep. 2021 Mar 5;21(3):15. PMID: 33666783.
    

28. ‣ Correa-Agudelo, E, Mersha TB, Hernández A, Branscum AJ, MacKinnon, NJ, Cuadros, DF (2021). Identification of Vulnerable Populations and Areas at Higher Risk of COVID-19-Related Mortality during the Early Stage of the Epidemic in the United States. Int. J. Environ. Res. Public Health 2021, 18(8), 4021. PMID: 32699858.
    

29. ‣ Mendy A, Wu X, Keller JL, Fassler CS, Apewokin S, Mersha TB, Xie C, Pinney (2021). Long-term exposure to fine particulate matter and hospitalization in COVID-19 patients. Respir Med. 178:106313.. PMID: 33550152.
    

2019

30. ‣ Gautam G, Afanador Y, Abebe T, López JE, Mersha TB (2019). Genome-wide analysis revealed sex-specific gene expression in asthmatics. Human Molecular Genetics, ddz074. In press.
    

31. ‣ Ghosh D, Bernstein JA, Hershey GKK, Rothenberg ME, Mersha TB (2019). Leveraging multilayered "omics" data for atopic dermatitis: a road map to precision medicine. Front Immunol. 12;9:2727. PMID: 30631320.
    

2018

32. ‣ Ding L, Li D, Wathen M, Altaye M, Mersha TB (2018). African ancestry is associated with cluster-based childhood asthma subphenotypes. BMC Med Genomics. 11(1):51. PMID: 29855310.
    

33. ‣ Ghandikota S, Hershey GKK, Mersha TB (2018). GENEASE: Real time bioinformatics tool for multi-omics and disease ontology exploration, analysis and visualization. Bioinformatics. 34(18):3160-3168. PMID: 29590301.
    

34. ‣ Kim Y, Hao J, Gautam Y, Mersha TB, Kang M (2018). DiffGRN: Differential gene regulatory network analysis. International Journal of Data Mining and Bioinformatics 20 (4): 362-379.
    

35. ‣ Harding K, Biks GA, Adefris M, Loehr J, Gashaye KT, Tilahun B, Volynski M, Garg S, Abebaw Z, Dessie K, Mersha TB (2018). A mobile health model supporting Ethiopia’s eHealth strategy. Digital Medicine 4 (2): 54-65.
    

36. ‣ Barnes JC, Liu H, Tanksley P, Motz R, Mersha, TB (2018). Every contact leaves a trace: contact with the criminal justice system, life outcomes, and the intersection with genetics. Current Opinion in Psychology 27:82-87. PMID: 30347286.
    

2017 and older

37. ‣ Gautam, Y, Altaye, M, Xie, C., Mersha TB (2017). AdmixPower: Statistical power and sample size estimation for mapping genetic loci in admixed populations. Genetics (Genetics Society of America). 207: 873–882. PMID: 28951529.
    

38. ‣ Johansson E, Biagini Myers JM, Martin LJ, He H, Pilipenko V, Mersha TB, Weirauch M, Salomonis N, Ryan P, LeMasters GK, Bernstein DI, Lockey J, Khurana Hershey GK (2017). KIF3A genetic variation is associated with pediatric asthma in the presence of eczema independent of allergic rhinitis. J Allergy Clin Immunol. 140(2):595-598. PMID: 28238750.
    

39. ‣ Mersha, TB, Cassidy C., Johansson E., Hershey GKK (2017). Shared genetic etiology and ancestry variations between asthma and major complex diseases. Journal of Allergy and Clinical Immunology Vol. 139, Issue 2, Supplement [AB84]. DOI: http://dx.doi.org.
    

40. ‣ Harding K, Mersha TB, Pham PT, Waterman AD, Webb FA, Vassalotti JA, Nicholas SB (2017). Health disparities in kidney transplantation for african americans. Am J Nephrol. 2017;46(2):165-175. PMID: 28787713.
    

41. ‣ Maglo KN, Mersha TB, Martin LJ (2106). Population Genomics and the Statistical Values of Race: An Interdisciplinary Perspective on the Biological Classification of Human Populations and Implications for Clinical Genetic Epidemiological Research. Front Genet. 7:22. PMID: 26925096.
    

42. ‣Gupta J, Johansson E, Bernstein JA, Chakraborty R, Hershey GKK, Rothenberg ME, Mersha TB. Resolving the etiology of atopic disorders by genetic analysis of racial ancestry. J Allergy Clin Immunol. 2016 Sep; 138(3):676-99. PMID: 27297995
    

43. ‣Mersha TB. Mapping asthma-associated variants in admixed populations. Front. Genet. 6:292. doi: 10.3389/fgene.2015.00292
    

44. ‣Ghosh D, Ding L, Sivaprasad U, Geh E, Biagini Myers J, Bernstein JA, Khurana Hershey GK, Mersha TB. Multiple Transcriptome Data Analysis Reveals Biologically Relevant Atopic Dermatitis Signature Genes and Pathways. PLoS One. 2015 Dec 30;10(12):e0144316. PMID: 26717000
    

45. ‣Mersha TB, Martin LJ, Biagini Myers JM, Kovacic MB, Lindsey M, Chen W, Hershey GKK. Genomic architecture of asthma differs by sex. Genomics. 106(1):15-22. PMID: 25817197
    

46. ‣Mersha TB, Abebe T. Self-reported race/ethnicity in the age of genomic research: its potential impact on understanding health disparities. Human Genomics 9:1. PMID: 25563503
    

47. ‣Butsch Kovacic M, Martin LJ, Biagini Myers JM, He H, Lindsey M, Mersha TB, Khurana Hershey GKK. Genetic approach identifies distinct asthma pathways in overweight vs normal weight children. Allergy. 70(8):1028-32. PMID: 26009928
    

48. ‣Sadhasivam S, Zhang X, Chidambaran V, Mavi J, Pilipenko V, Mersha TB, Meller J, Kaufman K, Martin L, McAuliffe J. Novel Associations between FAAH Genetic Variants and Postoperative Central Opioid related Adverse Effects. Pharmacogenomics J. 15(5):436-42. PMCID: PMC4492912
    

49. ‣Mersha TB, Ding L, He H, Alexander ES, Zhang X, Kurowski BG, Pilipenko V, Kottyan L, Martin LJ, Fardo DW. Impact of Population Stratification on Family-Based Association in an Admixed Population. Int J Genomics. 2015:501617. PMID: 26064873
    

50. ‣Biagini Myers JM, Martin LJ, Mersha TB, Bernstein DI, LeMasters GK, Khurana Herhsey GK. Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma. J Allergy Clin Immunol. [Epub ahead of print]. PMID: 24831437
    

51. ‣Pilipenko V, Kurowski B, Alexander ES, Ding L, Mersha TB, Fardo D, Martin LJ. Using Mendelian inheritance errors as quality control criteria in whole genome sequencing dataset. BMC Proceedings 2014, 8:S21
    

52. ‣Ding L, Kurowski BG, He H, Alexander ES, Mersha TB, Fardo DW, Zhang X, Pilipenko V, Kottyan L, Martin LJ. Modeling of Multivariate Longitudinal Phenotypes in Family Genetic Studies with Bayesian Multiplicity Adjustment. BMC Proceedings 2014, 8:S69
    

53. ‣Fardo DW, Zhang X, Ding L, He H, Kurowski B, Alexander E, Mersha TB, Pilipenko V, Kottyan L and Martin LJ. On Family-based Genome-wide Association Studies with Large Pedigrees: Observations and Recommendations. BMC Proceedings 2014, 8(Suppl 1):S26.
    

54. ‣Ding L, Abebe T, Beyene J, Wilke RA, Goldberg A, Woo JG, Martin LJ, Rothenberg ME, Rao M, Hershey GK, Chakraborty R, Mersha TB. Rank-based genome-wide analysis reveals the association of Ryanodine receptor-2 gene variants with childhood asthma among human populations. Hum Genomics. 2013 Jul 5;7:16.
    

55. ‣Bienengraeber M, Pellitteri-Hahn M, Hirata N, Baye TM, Bosnjak ZJ, Olivier M. Quantitative characterization of changes in the cardiac mitochondrial proteome during anesthetic preconditioning and ischemia. Physiol Genomics. 2013 Mar 1;45(5):163-70.
    

56. ‣Amirisetty S, Hershey GK, Baye TM. AncestrySNPminer: A bioinformatics tool to retrieve and develop ancestry informative SNP panels. Genomics. 2012 Jul;100(1):57-63.
    

57. ‣Feng Q, Wilke RA, Baye TM. Individualized risk for statin-induced myopathy-current knowledge, emerging challenges, and potential solutions. Pharamcogenomics 2012 Apr;13(5):579-94.
    

58. ‣Ding L, Wiener H, Abebe T, Altaye M, Go RC, Kercsmar C, Grabowski G, Martin LJ, Hershey GK, Chakorborty R, Baye TM. Comparison of measures of marker informativeness for ancestry and admixture mapping. BMC Genomics. 2011 Dec 20;12(1): 622.
    

59. ‣Baye TM, He H, Ding L, Kurowski BG, Zhang X, Martin LJ. Population structure analysis using rare and common functional variants. BMC Proceedings 2011 Nov 29, 5: S8.
    

60. ‣Ding L, Baye TM, He H, Zhang X, Kurowski BG and Martin LJ. Detection of associations with rare and common SNPs for quantitative traits: a nonparametric Bayes based approach. BMC Proceedings 2011 Nov 29, 5: S10.
    

61. ‣Zhang X, He H, Ding L, Baye TM, Kurowski B, Martin LJ. Family and population based data identify different rare causal variants. BMC Proceedings 2011 Nov 29, 5: S36.
    

62. ‣He H, Ding L, Zhang X, Baye TM, Kurowski BG, Martin LJ. Effect of population stratification analysis on false positive rates for common and rare variants. BMC Proceedings 2011 Nov 29, 5: S116.
    

63. ‣Kovacic MB, Myers JM, Wang N, Martin LJ, Lindsey M, Ericksen MB, He H, Patterson TL, Baye TM, Torgerson D, Roth LA, Gupta J, Sivaprasad U, Gibson AM, Tsoras AM, Hu D, Eng C, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Avila PC, Beckman K, Seibold MA, Gignoux C, Musaad SM, Chen W, Burchard EG, Hershey GK. Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences.. PLoS One. 2011 Aug 30; 6(8):e23714.
    

64. ‣Baye TM. Inter-chromosomal variation in the pattern of human population genetic structure. Human Genomics. 2011;5(4):220–240.
    

65. ‣Baye TM, Butsch Kovacic M, Biagini Myers JM, Martin LJ, Lindsey M, Patterson TL, He H, Ericksen MB, Gupta J, Tsoras AM, Lindsley A, Rothenberg ME, Wills-Karp M, Eissa NT, Borish L, Khurana Hershey GK. Differences in Candidate Gene Association between European Ancestry and African American Asthmatic Children. PLoS One. 2011 Feb 28;6(2):e16522.
    

66. ‣Baye TM, Abebe T, Wilke RA. Genotype-environment interactions and their translational implications. Personalized Medicine. 2011;8:59-70.
    

67. ‣Baye TM & Wilke RA. Mapping genes that predict treatment outcome in admixed populations. The Pharmacogenomics Journal. 2010 Oct; 10(6): 465-77. 
    

68. ‣Baye TM, Martin LJ, Khurana Hershey GK. Application of genetic/genomic approaches to allergic disorders. J Allergy Clin Immunol. 2010 Sep;126(3):425-36.
    

69. ‣Gawrieh S, Baye TM, Carless M, Wallace J, Komorowski R, Kleiner DE, Andris D, Makladi B, Cole R, Charlton M, Curran J, Dyer TD, Charlesworth J, Wilke R, Blangero J, Kissebah AH, Olivier M. Hepatic gene networks in morbidly obese patients with nonalcoholic fatty liver disease. Obes Surg. 2010 Dec;20(12):1698-709.
    

70. ‣Zhang Y, Smith EM, Baye TM, Zelembaba M, James R, Kissebah AH, Martin L, and Olivier M. Sequence variants in HTR5A affect triglyceride levels in obese individuals. Physiological Genomics. 2010; 42:168-176.
    

71. ‣Smith EM, Zhang Y, Baye TM, Gawrieh S, Cole R, Blangero J, Carless MA, Curran JE, Dyer TD, Abraham LJ, Moses EK, Kissebah AH, Martin LJ, Olivier M. INSIG1 influences obesity-related hypertriglyceridemia in humans. J Lipid Res. 2010 Apr;51(4):701-8.
    

72. ‣Baye TM, Wilke RA, Olivier M. Genomic and geographic distribution of private SNPs and pathways in human populations. Per Med. 2009 Nov 1;6(6):623-641.
    

73. ‣Zhang Y, Sonnenberg GE, Baye TM, Littrell J, Gunnell J, DeLaForest A, MacKinney E, Hillard CJ, Kissebah AH, Olivier M, Wilke RA. Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent. Pharmacogenomics. 2009 Dec;10(12):1929-39.
    

74. ‣Baye TM, Hemant K. Tiwari, and David B. Allison. Database mining for selection of SNP markers useful in admixture mapping. BMC BioData Mining. 2008; 2:1(1-8).
    

75. ‣Shriner D, Baye TM, Padilla MA, Zhang S, Vaughan LK, Loraine AE. Commonality of functional annotation: a method for prioritization of candidate genes from genome-wide linkage studies.Nucleic Acids Res. e26, 2008.
    

76. ‣Baye TM, Zhang S, Smith E, Gunnell J, Hillard CJ, McCarty D, Myklebust J, James R, Kissebah AH, Olivier M and Wilke RA. Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index. Pharmacogenomics. 2008; 9(11):1647-1656.
    

77. ‣Tesfaye M. Baye, Rodney T. Perry, Howard W. Wiener, Zuomin Chen, Lindy Harrell, Rodney Go. Candidate gene discovery procedure after follow-up confirmatory analyses of candidate regions of interests for Alzheimer’s disease in the NIMH sibling dataset.Dis Markers. 2007; 24:293-309.