Mouse
Human

Definition

Sub cell type

Cell signatures

Explore in CellRef^new

Query another gene in CellRef

Query signatures of LGEA datasets

Query images by marker

Definition

Sub cell type

Cell signatures

Explore in CellRef^new

Query another gene in CellRef

Query signatures of LGEA datasets

Query images by marker

LGEA Web Portal (LungMAP Phase 3)

LGEA phase 3
LGEA
LungMAP
About

Region at a glance

Cell at a glance

Gene at a glance

Single cell reference

Mouse
Human

Search:

Pan H, Deutsch GH, Wert SE; Ontology Subcommittee; NHLBI Molecular Atlas of Lung Development Program Consortium. Comprehensive anatomic ontologies for lung development: A comparison of alveolar formation and maturation within mouse and human lung. J Biomed Semantics. 2019;.

Basal
(TP63/KRT5)

AT2 (NKX2-1)
AT1 (AGER)
Myofibroblast (ACTA2)

Club (SCGB1A1)
Airway Epithelial (NKX2.1)
Ciliated (TUBA4A)

Airway Epithelial (SOX2)
Cartilage (SOX9)

AT2 (NKX2.1)
Endothelial (PECAM1)
Vascular smooth muscle (ACTA2)

Goblet (MUC5B)
Myoepithelial (KRT14)

Cell legend ( click cell for details )

Epithelium

Airway Epithelial

Basal Ciliated Goblet Secretory
Ionocyte PNEC Myoepithelial Tuft
Serous Mucous BASC
Terminal ciliated duct basal cells RAS Deuterosomal Suprabasal

Distal Epithelial

AT1 AT2 AT1/AT2 SOX9+

Endothelium

Vascular endothelial cell

Capillary( Cap1 Cap2)
Arterial Venous SVEC

Lymphatic endothelial cell
Endothelial progenitor cell

Immune

Myeloid

Marcophage( aMac iMac)
Monocyte( pMon iMon)
Dendritic( cDC1 cDC2 pDC
maDC)
Basophil Mast Eosinophil
Neutrophil
Megakaryocyte/Platelet

Lymphocyte

T cell Treg CD4+T cell CD8+T cell B cell Plasma NK
ILC( ILC1 ILC2 ILC3)

Mesenchyme

Alveolar fibroblast( AF1 AF2)
Lipofibroblast Pericyte
Smooth muscle( VSMC ASMC)
Secondary crest myofibroblast cell
Proliferative mesenchymal progenitor
Chondrocytes Mesothelium

Goblet (MUC5B)
Ciliated (TUBA4A)

Neuroendocrine (GRP)
Airway Epithelial (SOX2)
Nerve (TUBB3)

AT2 (NKX2.1)
Macrophage (CD68)
Myofibroblast (ACTA2)

AT2 (SFTPC)
CLUB (SCGB1A1)
Bronchial Smooth Muscle (ACTA2)

Lymphatic Endothelial (LYVE1)
Airway Epithelial (NKX2.1)
Bronchial Smooth Muscle (ACTA2)

AT2 (NKX2.1)
Endothelial (PECAM1)
Myofibroblast (ACTA2)

Proximal airway
(KRT14, SOX2, KRT5)

Terminal bronchiole
(TP63, NKX2.1, KRT5)

Submucosal gland
(KRT14, MUC5B, TUBA4A)

Bronchiole
(SYP, SOX2, TUBB3)

Alveoli
(NKX2.1, AGER, ACTA2)

To cite LGEA Web Portal in your publications you can use the following reference:

1. Du Y, Ouyang W, Kitzmiller JA, Guo M, Zhao S, Whitsett JA, Xu Y. Lung Gene Expression Analysis Web Portal Version 3: Lung-at-a-Glance. Am J Respir Cell Mol Biol. 2021 Jan;64(1):146-149.