| Category |
Details |
| Cell Type Desc. |
The pulmonary system contains a variety of epithelial cell populations that each reside in distinct anatomical locations. Basal (Krt4, Krt15), secretory, and ciliated cells (Foxj1) line the trachea and the proximal conducting airways; neuroendocrine cells are present in small numbers. The nonciliated, columnar Club cells (Scgb1a1) comprise the majority of the bronchiolar and terminal bronchiolar epithelium in mice, and alveolar type I (AT1: Pdpn, Hopx) and type II (AT2: Sftpb, Sftpc) cells constitute the alveolar epithelium (Bannister, 1999).
The pulmonary system contains a variety of epithelial cell populations that each reside in distinct anatomical locations. Basal (Krt4, Krt15), secretory, and ciliated cells (Foxj1) line the trachea and the proximal conducting airways; neuroendocrine cells are present in small numbers. The nonciliated, columnar Club cells (Scgb1a1) comprise the majority of the bronchiolar and terminal bronchiolar epithelium in mice, and alveolar type I (AT1: Pdpn, Hopx) and type II (AT2: Sftpb, Sftpc) cells constitute the alveolar epithelium (Bannister, 1999).
The pulmonary system contains a variety of epithelial cell populations that each reside in distinct anatomical locations. Basal (Krt4, Krt15), secretory, and ciliated cells (Foxj1) line the trachea and the proximal conducting airways; neuroendocrine cells are present in small numbers. The nonciliated, columnar Club cells (Scgb1a1) comprise the majority of the bronchiolar and terminal bronchiolar epithelium in mice, and alveolar type I (AT1: Pdpn, Hopx) and type II (AT2: Sftpb, Sftpc) cells constitute the alveolar epithelium (Bannister, 1999).
The pulmonary system contains a variety of epithelial cell populations that each reside in distinct anatomical locations. Basal (Krt4, Krt15), secretory, and ciliated cells (Foxj1) line the trachea and the proximal conducting airways; neuroendocrine cells are present in small numbers. The nonciliated, columnar Club cells (Scgb1a1) comprise the majority of the bronchiolar and terminal bronchiolar epithelium in mice, and alveolar type I (AT1: Pdpn, Hopx) and type II (AT2: Sftpb, Sftpc) cells constitute the alveolar epithelium (Bannister, 1999).
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| Signature Genes |
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| External Resources |
LifeMap Discovery
EMBL-EBI: Expression Atlas
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Heatmap was generated using top 30 putative marker genes for each cell lineage inferred from the E18.5 single cell transcriptomes as a function of the multiple testing corrected p-value for each gene. [PubMed]