a. Multiple cohorts analysis using adalimumab +/- concomitant drugs
Search adalimumab AEs without confounding drugsFig. 10.1 – Include adalimumab and exclude methotrexate and glucocorticoids Search adalimumab + methotrexate without steroidsFig. 10.2 - Create new set with patients on both adalimumab and methotrexate but no glucocorticoids Fig. 10.3 - Create combinatorial set with glucocorticoids Include rheumatoid arthritis and exclude cancer patientsFig. 10.4 - Select patients with rheumatoid arthritis Fig. 10.5 - exclude patients with any indications of cancer Fig. 10.6 - excluded cancer types Analyze differential risk profiles across adults and elderly (males + females)Fig. 10.7 - Select demographic subgroups View and Change FiltersFig. 10.8 - view and change filters Fig. 10.9 - visualize the results as a heatmap VisualizeFig. 10.10 - Change Heatmap color-scheme Fig. 10.11 - Set the heatmap min-max range Fig. 10.12 - Customize the heatmap
